Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 4/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6052407 | 0.84 | GAA (0.60) | MAPTGAAHSD17B10LMNAKDM4E | |
| SCHEMBL6052414 | 0.81 | GAA (0.50) | MAPTGAAHSD17B10LMNAKDM4E | |
| SCHEMBL5857643 | 0.79 | MAPT (0.53) | MAPTGAAHSD17B10LMNAKDM4E | |
| SCHEMBL28294734 | 0.78 | LMNA (0.41) | MAPTGAAHSD17B10LMNAKDM4E | |
| SCHEMBL28296408 | 0.77 | LTA4H (0.43) | MAPTGAAHSD17B10LMNAKDM4E | |
| Ethoxycarbonyl Group SCHEMBL28873297 | 0.76 | GAA (0.48) | MAPTGAAHSD17B10LMNAKDM4E | |
| SCHEMBL28957487 | 0.76 | GAA (0.43) | MAPTGAAHSD17B10LMNAKDM4E | |
| SCHEMBL28294730 | 0.76 | ALDH1A1 (0.53) | MAPTHSD17B10LMNAKDM4EDRD2 | |
| SCHEMBL5654064 | 0.74 | MAPT (0.63) | MAPTGAAHSD17B10LMNAKDM4E | |
| SCHEMBL29703766 | 0.74 | MAPT (0.63) | MAPTGAAHSD17B10LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651297-A | A kind of N- benzyl-N- aryl sulfonic acid amides analog derivative and preparation and application | 杭州壹瑞医药科技有限公司 | 2019-04-19 | — | — | CN | disclosed |