Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | NPY2R | P49146 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28296408 | 0.82 | LTA4H (0.43) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| Ethoxycarbonyl Group SCHEMBL28294731 | 0.81 | ALDH1A1 (0.52) | ALDH1A1RXFP1MEN1KMT2ANPSR1 | |
| SCHEMBL28744889 | 0.77 | MAPT (0.58) | ALDH1A1RXFP1MEN1KMT2ANPSR1 | |
| SCHEMBL28294734 | 0.77 | LMNA (0.41) | ALDH1A1RXFP1MEN1KMT2ANPSR1 | |
| SCHEMBL28296378 | 0.76 | DRD2 (0.38) | ALDH1A1KMT2AMAPTDRD4DRD2 | |
| SCHEMBL28873296 | 0.76 | MAPT (0.50) | ALDH1A1MAPTHSD17B10SMN1; SMN2DRD2 | |
| SCHEMBL28957487 | 0.75 | GAA (0.43) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL27714024 | 0.72 | MAPT (0.52) | ALDH1A1RXFP1MEN1KMT2AMAPT | |
| SCHEMBL5858954 | 0.70 | ALDH1A1 (0.68) | ALDH1A1RXFP1MEN1KMT2ANPSR1 | |
| SCHEMBL5857776 | 0.70 | HTR2A (0.48) | ALDH1A1RXFP1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651297-A | A kind of N- benzyl-N- aryl sulfonic acid amides analog derivative and preparation and application | 杭州壹瑞医药科技有限公司 | 2019-04-19 | — | — | CN | disclosed |