Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28957487 | 0.90 | GAA (0.43) | HTR6GAAALDH1A1HPGDKDM4E | |
| SCHEMBL28294734 | 0.83 | LMNA (0.41) | GAAHTR2AALDH1A1HPGDKDM4E | |
| SCHEMBL28294730 | 0.82 | ALDH1A1 (0.53) | HTR2AALDH1A1HPGDKDM4EDRD2 | |
| Ethoxycarbonyl Group SCHEMBL28296409 | 0.80 | ALDH1A1 (0.41) | HTR6GAAHTR2AALDH1A1HPGD | |
| SCHEMBL28873296 | 0.77 | MAPT (0.50) | GAAHTR2AALDH1A1KDM4EDRD2 | |
| SCHEMBL28294727 | 0.75 | NR3C1 (0.42) | HTR6GAAHTR2AALDH1A1HPGD | |
| Ethoxycarbonyl Group SCHEMBL28957488 | 0.71 | GAA (0.42) | HTR6GAAALDH1A1HPGDKDM4E | |
| SCHEMBL28296378 | 0.70 | DRD2 (0.38) | HTR6GAAHTR2AALDH1A1KDM4E | |
| SCHEMBL22273612 | 0.70 | KDM4E (0.42) | HTR6GAAHTR2AALDH1A1HPGD | |
| SCHEMBL7262207 | 0.69 | KCNH2 (0.57) | HTR2ADRD2HTR1AHTR7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651297-A | A kind of N- benzyl-N- aryl sulfonic acid amides analog derivative and preparation and application | 杭州壹瑞医药科技有限公司 | 2019-04-19 | — | — | CN | disclosed |