Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218287 | 0.88 | KCNH2 (0.61) | KCNH2PGRLTA4HALDH1A1CYP3A4 | |
| SCHEMBL23312079 | 0.84 | PGR (0.57) | KCNH2PGRLTA4HALDH1A1CYP3A4 | |
| SCHEMBL10013481 | 0.84 | PGR (0.57) | KCNH2PGRLTA4HALDH1A1CYP3A4 | |
| SCHEMBL5518925 | 0.82 | PGR (0.56) | KCNH2PGRLTA4HHSD17B10ALDH1A1 | |
| SCHEMBL18770051 | 0.82 | PGR (0.56) | KCNH2PGRLTA4HHSD17B10ALDH1A1 | |
| SCHEMBL26259864 | 0.82 | PGR (0.59) | KCNH2PGRLTA4HALDH1A1CYP3A4 | |
| SCHEMBL11073783 | 0.81 | PGR (0.54) | KCNH2PGRLTA4HHSD17B10ALDH1A1 | |
| SCHEMBL9912108 | 0.81 | KCNH2 (0.54) | KCNH2PGRLTA4HHSD17B10CYP3A4 | |
| SCHEMBL830311 | 0.80 | LTA4H (0.63) | KCNH2LTA4HHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL1015792 | 0.79 | ATAD2 (0.63) | KCNH2LTA4HHSD17B10ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260122-B | Naphthothiazole derivative and synthesis method thereof | 陕西科技大学 | 2024-05-28 | — | — | CN | claimed |
| CN-115260122-A | Naphthothiazole derivative and synthesis method thereof | 陕西科技大学 | 2022-11-01 | — | — | CN | claimed |
| CN-115260122-B | Naphthothiazole derivative and synthesis method thereof | 陕西科技大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-115260122-A | Naphthothiazole derivative and synthesis method thereof | 陕西科技大学 | 2022-11-01 | — | — | CN | disclosed |