Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.41 |
| ▸ | TUBB | P07437 | 5/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5567677 | 0.84 | BRD4 (0.53) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Ethoxycarbonyl Group SCHEMBL28291587 | 0.81 | ALDH1A1 (0.40) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Ethoxycarbonyl Group SCHEMBL28338776 | 0.78 | P2RX7 (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Ethoxycarbonyl Group SCHEMBL28678157 | 0.78 | TUBB4A (0.43) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Ethoxycarbonyl Group SCHEMBL28880744 | 0.77 | JAK2 (0.48) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Ethoxycarbonyl Group SCHEMBL27551543 | 0.73 | NR3C1 (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Ethoxycarbonyl Group SCHEMBL27908804 | 0.73 | HSD17B10 (0.36) | BRD4MEN1KMT2A | |
| Ethoxycarbonyl Group SCHEMBL27309525 | 0.72 | RHEB (0.43) | GRIN1 | |
| Ethoxycarbonyl Group SCHEMBL28994910 | 0.72 | TLR8 (0.42) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Ethoxycarbonyl Group SCHEMBL27771265 | 0.70 | LMNA (0.41) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102952062-A | Substituted benzoheterocyclic compounds and preparation method and application thereof | INST MEDICINAL BIOTECHNOLOGY | 2013-03-06 | — | — | CN | claimed |
| CN-102952062-B | Replace benzo-heterocycle compound and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2016-06-08 | — | — | CN | disclosed |
| CN-102952062-A | Substituted benzoheterocyclic compounds and preparation method and application thereof | INST MEDICINAL BIOTECHNOLOGY | 2013-03-06 | — | — | CN | disclosed |