Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893632 | 1.00 | ADRB2 (0.37) | ADRB2P2RY1NPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL28889277 | 0.91 | P2RY1 (0.38) | ADRB2P2RY1ALDH1A1L3MBTL1GAA | |
| SCHEMBL29893566 | 0.88 | ADRB2 (0.39) | ADRB2NPSR1ALDH1A1L3MBTL1GAA | |
| SCHEMBL28889291 | 0.88 | ADRB2 (0.39) | ADRB2NPSR1ALDH1A1L3MBTL1GAA | |
| SCHEMBL28889349 | 0.85 | P2RY1 (0.41) | ADRB2P2RY1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL28889200 | 0.84 | ADRB2 (0.41) | ADRB2NPSR1ALDH1A1L3MBTL1GAA | |
| SCHEMBL28889381 | 0.80 | ADRB2 (0.39) | ADRB2P2RY1ALDH1A1L3MBTL1 | |
| SCHEMBL29893596 | 0.80 | ADRB2 (0.39) | ADRB2NPSR1ALDH1A1L3MBTL1GAA | |
| SCHEMBL28889374 | 0.80 | ADRB2 (0.39) | ADRB2NPSR1ALDH1A1L3MBTL1GAA | |
| SCHEMBL28889233 | 0.78 | PHGDH (0.41) | ADRB2NPSR1ALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |