Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 12/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
| ▸ | NEK4 | P51957 | 1/20 | 0.37 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.37 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.37 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28889277 | 0.90 | P2RY1 (0.38) | P2RY1ADRB2KDRCLK2IRAK1 | |
| SCHEMBL28889382 | 0.87 | ADRB2 (0.39) | P2RY1MEN1KMT2AADRB2KDR | |
| SCHEMBL29893632 | 0.85 | ADRB2 (0.37) | P2RY1MEN1KMT2AADRB2LMNA | |
| SCHEMBL28889238 | 0.85 | ADRB2 (0.37) | P2RY1MEN1KMT2AADRB2LMNA | |
| SCHEMBL28889187 | 0.83 | MEN1 (0.40) | MEN1KMT2AADRB2LMNAPOLB | |
| SCHEMBL28889178 | 0.83 | HDAC4 (0.43) | P2RY1MEN1KMT2AADRB2LMNA | |
| SCHEMBL28889281 | 0.83 | KMT2A (0.40) | P2RY1MEN1KMT2AADRB2LMNA | |
| SCHEMBL28889381 | 0.83 | ADRB2 (0.39) | P2RY1ADRB2ALDH1A1L3MBTL1 | |
| SCHEMBL28889319 | 0.82 | ADRB2 (0.41) | MEN1KMT2AADRB2KDRALDH1A1 | |
| SCHEMBL29941697 | 0.80 | MEN1 (0.49) | MEN1KMT2AADRB2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |