Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | CBLB | Q13191 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941818 | 0.88 | HDAC4 (0.41) | HDAC4HDAC7HDAC5AURKAADRB2 | |
| SCHEMBL28889212 | 0.87 | HDAC4 (0.40) | HDAC4HDAC7HDAC5AURKAADRB2 | |
| SCHEMBL28889342 | 0.86 | OPRM1 (0.40) | HDAC4HDAC7HDAC5ADRB2OPRM1 | |
| SCHEMBL28889214 | 0.86 | HDAC4 (0.39) | HDAC4HDAC7HDAC5AURKAADRB2 | |
| SCHEMBL28889170 | 0.85 | HDAC4 (0.43) | HDAC4HDAC7HDAC5AURKAADRB2 | |
| SCHEMBL29893770 | 0.85 | HDAC4 (0.43) | HDAC4HDAC7HDAC5AURKAADRB2 | |
| SCHEMBL28889250 | 0.85 | MEN1 (0.44) | HDAC4HDAC7HDAC5AURKAADRB2 | |
| SCHEMBL29893755 | 0.85 | MEN1 (0.44) | HDAC4HDAC7HDAC5AURKAADRB2 | |
| SCHEMBL28889290 | 0.85 | LMNA (0.40) | HDAC4HDAC7HDAC5OPRL1KMT2A | |
| SCHEMBL29942056 | 0.82 | ALDH1A1 (0.43) | HDAC4HDAC7HDAC5ADRB2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |