Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002669 | 1.00 | LMNA (0.44) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL28959518 | 0.89 | LMNA (0.42) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL28959464 | 0.84 | L3MBTL1 (0.40) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL28892522 | 0.82 | MAOA (0.40) | KMT2AMAOAMEN1MAPTHTT | |
| SCHEMBL30002412 | 0.82 | MAOA (0.40) | KMT2AMAOAMEN1MAPTHTT | |
| SCHEMBL30002055 | 0.82 | SCN1A (0.46) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL28893045 | 0.82 | SCN1A (0.46) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL28892166 | 0.81 | L3MBTL1 (0.39) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL28892922 | 0.81 | ALDH1A1 (0.43) | LMNACASP3SENP8SENP7SENP6 | |
| SCHEMBL30002047 | 0.81 | ALDH1A1 (0.43) | LMNACASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |