Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892522 | 1.00 | MAOA (0.40) | MAOAMAPTGAASMN1; SMN2TDP1 | |
| SCHEMBL30002556 | 0.88 | MAOA (0.39) | MAOAMAPTGAASMN1; SMN2TDP1 | |
| SCHEMBL28892234 | 0.88 | MAOA (0.39) | MAOAMAPTGAASMN1; SMN2TDP1 | |
| SCHEMBL28892139 | 0.82 | LMNA (0.44) | MAOAMAPTGAATDP1TRPA1 | |
| SCHEMBL30002669 | 0.82 | LMNA (0.44) | MAOAMAPTGAATDP1TRPA1 | |
| SCHEMBL28892670 | 0.82 | KIT (0.37) | MAOAMAPTGAASMN1; SMN2TDP1 | |
| SCHEMBL30002702 | 0.82 | KIT (0.37) | MAOAMAPTGAASMN1; SMN2TDP1 | |
| SCHEMBL30002548 | 0.80 | SCN1A (0.47) | MAOAMAPTGAASMN1; SMN2TDP1 | |
| SCHEMBL28892526 | 0.80 | SCN1A (0.47) | MAOAMAPTGAASMN1; SMN2TDP1 | |
| SCHEMBL30002638 | 0.79 | NSD2 (0.41) | MAOAMAPTGAASMN1; SMN2KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |