Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288943 | 0.78 | RAB9A (0.44) | RAB9ACYP1A2CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL4704457 | 0.76 | L3MBTL1 (0.44) | RAB9ACYP1A2CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL3930322 | 0.69 | TDP1 (0.58) | RAB9ACYP1A2CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL7567608 | 0.69 | CASP1 (0.44) | RAB9ACYP1A2CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL7567614 | 0.68 | RAB9A (0.34) | RAB9ACYP1A2CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL3934013 | 0.66 | NPC1 (0.53) | RAB9ASMN1; SMN2ALDH1A1NPC1LMNA | |
| SCHEMBL7221909 | 0.65 | ALDH1A1 (0.41) | ALDH1A1HSD17B10 | |
| SCHEMBL732122 | 0.65 | ALDH1A1 (0.41) | RAB9ASMN1; SMN2ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL30565424 | 0.65 | TSHR (0.53) | RAB9ACYP1A2CYP2C19SMN1; SMN2ALDH1A1 | |
| Benzo[D]Thiazole SCHEMBL28677081 | 0.64 | LMNA (0.52) | RAB9ACYP1A2CYP2C19SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427451-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BioLab Corporation (JP) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128685-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2010-11-11 | — | — | WO | disclosed |