Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413489 | 0.87 | CASP1 (0.44) | CASP1CCNE1CDK2MEN1KMT2A | |
| SCHEMBL6136686 | 0.84 | CASP1 (0.46) | CASP1CCNE1CDK2MEN1KMT2A | |
| SCHEMBL288943 | 0.78 | RAB9A (0.44) | CASP1CCNE1CDK2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7571648 | 0.77 | TSHR (0.41) | MEN1KMT2AL3MBTL1MAPK1NPSR1 | |
| SCHEMBL4704457 | 0.77 | L3MBTL1 (0.44) | CASP1CCNE1CDK2SMN1; SMN2ALDH1A1 | |
| SCHEMBL7576535 | 0.76 | ALDH1A1 (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL7572653 | 0.74 | ALDH1A1 (0.58) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL7573224 | 0.73 | CNR2 (0.58) | SMN1; SMN2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7571824 | 0.70 | EPHX2 (0.51) | ALDH1A1RAB9AMTNR1A | |
| SCHEMBL7574286 | 0.70 | CNR2 (0.46) | SMN1; SMN2CYP1A2KDM4ECYP2D6PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |