Sugi Predict

Sugi Predict / Compounds / SCHEMBL2890201

SCHEMBL2890201

SCHEMBL2890201

O=[N+]([O-])C=CN1CCOCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MITF O75030 2/20 0.46
▸ ALDH1A1 P00352 8/20 0.39
▸ MAPT P10636 7/20 0.39
▸ SMN1; SMN2 Q16637 4/20 0.39
▸ HPGD P15428 2/20 0.39
▸ NTSR1 P30989 1/20 0.39
▸ RECQL P46063 2/20 0.37
▸ KMT2A Q03164 3/20 0.35
▸ MAPK1 P28482 2/20 0.35
▸ HTT P42858 1/20 0.35
▸ ATM Q13315 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ NPC1 O15118 2/20 0.34
▸ RAB9A P51151 2/20 0.34
▸ PKM P14618 1/20 0.34
▸ USP2 O75604 2/20 0.33
▸ ALOX12 P18054 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ POLB P06746 2/20 0.33
▸ CTSB P07858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9041209 1.00 MITF (0.46) MITFALDH1A1MAPTSMN1; SMN2HPGD
SCHEMBL6851679 0.81 MITF (0.35) MITFALDH1A1MAPTSMN1; SMN2KMT2A
SCHEMBL13105362 0.74 — —
SCHEMBL10808510 0.67 CYP2C19 (0.38) ALDH1A1KMT2AMAPK1HTTMEN1
SCHEMBL9475147 0.67 ADRB1 (0.30) —
SCHEMBL14582189 0.65 RECQL (0.48) ALDH1A1MAPTSMN1; SMN2HPGDRECQL
SCHEMBL644944 0.65 RECQL (0.48) ALDH1A1MAPTSMN1; SMN2HPGDRECQL
SCHEMBL10587411 0.64 ALDH1A1 (0.35) MITFALDH1A1MAPTSMN1; SMN2RECQL
SCHEMBL9142690 0.64 — —
SCHEMBL454530 0.64 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608836-A1 MICROBIOCIDAL HETEROBICYCLIC DIHYDROOXADIAZINE DERIVATIVES Syngenta Crop Protection AG (CH) 2025-09-03 — — EP disclosed
US-20250034141-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-01-30 — — US disclosed
US-12152027-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-11-26 — — US disclosed
WO-2024089191-A1 MICROBIOCIDAL HETEROBICYCLIC DIHYDROOXADIAZINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-05-02 — — WO disclosed
US-11897879-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-02-13 — — US disclosed
US-20230192685-A1 METHOD FOR PRODUCING HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-06-22 — — US disclosed
EP-4163280-A1 METHOD FOR PRODUCING HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2023-04-12 — — EP disclosed
US-20220089595-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICALS CO (JP) 2022-03-24 — — US disclosed
US-20220048916-A1 HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-02-17 — — US disclosed
US-11230545-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-01-25 — — US disclosed
EP-0354994-B1 Quinoline derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-01-25 — — EP disclosed
US-5264454-A Enzyme inhibitors, anticholesterol agents TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-11-23 — — US disclosed
US-5256782-A For anticholesterol agents TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-10-26 — — US disclosed
US-5254565-A Enzyme inhibitors; anticholesterol agents TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-10-19 — — US disclosed
US-5143919-A Acyl-CoA:cholesterol acyltransferase inhibitors; anticholesterol agents; TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-01 — — US disclosed
EP-0481243-A1 Tricyclic heterocyclic compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1992-04-22 — — EP disclosed
EP-0472116-A1 Thienopyridine Derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1992-02-26 — — EP disclosed
EP-0400842-A1 Triazole pesticides SCHERING AGROCHEMICALS LIMITED (GB) 1990-12-05 — — EP disclosed
EP-0354994-A2 Quinoline derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1990-02-21 — — EP disclosed
CN-1039416-A Quinoline and preparation thereof and purposes TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1990-02-07 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220089595-A1 HETEROCYCLIC COMPOUND MALT1, SQSTM1, PPM1D MITF 713/4885ALDH1A1 1199/4885MAPT 1683/4885
US-20250034141-A1 HETEROCYCLIC COMPOUND MALT1, SQSTM1, PPM1D MITF 713/4885ALDH1A1 1199/4885MAPT 1683/4885
US-11230545-B2 Heterocyclic compound MALT1, SQSTM1, PPM1D MITF 713/4885ALDH1A1 1199/4885MAPT 1683/4885
US-20230192685-A1 METHOD FOR PRODUCING HETEROCYCLIC COMPOUND MALT1, CYP51A1, ME1 MITF 96/4885ALDH1A1 1289/4885MAPT 2851/4885
US-12152027-B2 Heterocyclic compound MALT1, SQSTM1, PPM1D MITF 713/4885ALDH1A1 1199/4885MAPT 1683/4885
US-20220048916-A1 HETEROCYCLIC COMPOUND MALT1, SQSTM1, PPM1D MITF 713/4885ALDH1A1 1199/4885MAPT 1683/4885
US-11897879-B2 Heterocyclic compound MALT1, SQSTM1, PPM1D MITF 713/4885ALDH1A1 1199/4885MAPT 1683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.