Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL849055 | 0.77 | KDM4E (0.39) | MAPTLMNAKDM4EALDH1A1ALOX15 | |
| SCHEMBL14529071 | 0.76 | ALDH1A1 (0.36) | MAPTNPC1GAALMNAKDM4E | |
| SCHEMBL851360 | 0.74 | HTT (0.35) | MAPTLMNAALDH1A1HTTCYP1A2 | |
| SCHEMBL13552299 | 0.74 | TRPA1 (0.36) | MAPTGAALMNAALDH1A1HTT | |
| SCHEMBL849826 | 0.72 | ALDH1A1 (0.46) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL850422 | 0.69 | HDAC1 (0.47) | MAPTLMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL849709 | 0.69 | LMNA (0.38) | MAPTNPC1GAALMNAKDM4E | |
| SCHEMBL879760 | 0.69 | TSHR (0.33) | MAPTLMNAALDH1A1ALOX15TSHR | |
| SCHEMBL8630814 | 0.69 | PTGS2 (0.36) | NPC1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL16637264 | 0.69 | ALDH1A1 (0.33) | LMNAALDH1A1ALOX15TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417999-B | One-dimensional polyrotaxane constructed based on coordination boron-nitrogen bond, and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2023-07-07 | — | — | CN | disclosed |
| CN-115417999-A | One-dimensional polyrotaxane constructed based on coordinated boron-nitrogen bond and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2022-12-02 | — | — | CN | disclosed |