SCHEMBL849709

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9360724	0.81	ALDH1A1 (0.46)	LMNAKCNH3ALDH1A1MAPTRAB9A
	SCHEMBL849929	0.79	KCNH3 (0.40)	LMNAKCNH3ALDH1A1MAPTRAB9A
	SCHEMBL28564265	0.78	THRB (0.52)	LMNAKCNH3ALDH1A1MAPTRAB9A
	SCHEMBL13552299	0.78	TRPA1 (0.36)	LMNAALDH1A1MAPTCYP1A2CYP2C19
	SCHEMBL851360	0.78	HTT (0.35)	LMNAALDH1A1MAPTCYP1A2CYP2C19
	SCHEMBL879838	0.78	TSHR (0.36)	LMNAALDH1A1MAPTRAB9ACYP1A2
	SCHEMBL29136362	0.77	KCNH3 (0.44)	LMNAKCNH3ALDH1A1MAPTRAB9A
	SCHEMBL6334634	0.77	ALDH1A1 (0.45)	LMNAKCNH3ALDH1A1MAPTRAB9A
	SCHEMBL849826	0.76	ALDH1A1 (0.46)	LMNAALDH1A1MAPTCYP1A2HTT
	SCHEMBL12208099	0.75	DUT (0.30)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.