SCHEMBL28906996

SCHEMBL28906996

Cc1cc(F)cc2c1[nH]c1c(C)cc(F)cc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.41
PGR P06401 2/20 0.41
MAPT P10636 2/20 0.38
GRIN2D O15399 2/20 0.35
GRIN3B O60391 2/20 0.35
GRIN1 Q05586 2/20 0.35
GRIN2A Q12879 2/20 0.35
GRIN2B Q13224 2/20 0.35
GRIN2C Q14957 2/20 0.35
GRIN3A Q8TCU5 2/20 0.35
HSD17B10 Q99714 1/20 0.35
KIF11 P52732 1/20 0.34
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
GPR84 Q9NQS5 1/20 0.32
TNKS2 Q9H2K2 2/20 0.32
TNKS O95271 1/20 0.32
PARP1 P09874 1/20 0.32
ABCB1 P08183 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31223258 1.00 AR (0.41) ARPGRMAPTGRIN2DGRIN3B
SCHEMBL6826973 0.80 KIF11 (0.59) MAPTHSD17B10KIF11TNKS2PARP1
SCHEMBL5794646 0.78 PGR (0.43) ARPGRMAPTGRIN2DGRIN3B
SCHEMBL14698434 0.75 F2 (0.37) ARPGRGRIN2DGRIN3BGRIN1
SCHEMBL6826950 0.75 MAPT (0.42) ARMAPTHSD17B10PARP1ALDH1A1
SCHEMBL30858656 0.75 AR (0.48) ARMAPTGPR84ALDH1A1
SCHEMBL29507658 0.74 GPR84 (0.48) ARPGRGPR84ALDH1A1
SCHEMBL29364610 0.74 MAPT (0.61) ARMAPTGRIN2DGRIN3BGRIN1
SCHEMBL28706409 0.74 GPR84 (0.48) ARPGRGPR84ALDH1A1
SCHEMBL29975937 0.74 MAPT (0.61) ARMAPTGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112142725-A Organic electroluminescent material based on xanthone and application thereof in preparing OLED (organic light emitting diode) 华南理工大学 2020-12-29 CN disclosed