Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24375495 | 0.80 | IRAK4 (0.41) | L3MBTL1LMNASMN1; SMN2IRAK4CHEK1 | |
| SCHEMBL3545517 | 0.79 | PDK1 (0.39) | L3MBTL1LMNASMN1; SMN2ARMEN1 | |
| SCHEMBL3551339 | 0.70 | MTOR (0.37) | LMNAALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL4463690 | 0.70 | LMNA (0.68) | LMNASMN1; SMN2ARMEN1KMT2A | |
| SCHEMBL1177308 | 0.66 | PIK3CA (0.64) | SMN1; SMN2NPC1RAB9AALDH1A1PIK3CD | |
| SCHEMBL27668588 | 0.66 | LMNA (0.43) | LMNASMN1; SMN2ALDH1A1MAPTPKM | |
| SCHEMBL13634271 | 0.66 | IRAK4 (0.39) | MAPTIRAK4CHEK1ATRPDCD1 | |
| SCHEMBL21889136 | 0.66 | LMNA (0.61) | LMNAIRAK4CHEK1ATRPDCD1 | |
| SCHEMBL28003161 | 0.65 | MTOR (0.41) | LMNASMN1; SMN2ARNPC1RAB9A | |
| SCHEMBL24375533 | 0.65 | MTOR (0.44) | IRAK4CHEK1ATRPDCD1ATRIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113105411-A | Hydrazone amide derivatives and pharmaceutical compositions | 深圳市三启药物开发有限公司 | 2021-07-13 | — | — | CN | claimed |
| CN-110229118-B | Hydrazone amide derivative and application thereof in preparation of anti-osteoporosis drugs | 深圳市三启药物开发有限公司 | 2021-03-02 | — | — | CN | claimed |
| CN-110229118-B | Hydrazone amide derivative and application thereof in preparation of anti-osteoporosis drugs | 深圳市三启药物开发有限公司 | 2021-03-02 | — | — | CN | disclosed |