Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | PDE4A | P27815 | 9/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28527640 | 0.87 | CSF1R (0.59) | CSF1RKCNH2PDE4APDE4BPDE4C | |
| SCHEMBL28527127 | 0.86 | CSF1R (0.59) | CSF1RKCNH2PDE4A | |
| SCHEMBL28530641 | 0.83 | CSF1R (0.62) | CSF1RKCNH2PDE4A | |
| SCHEMBL28538513 | 0.82 | CSF1R (0.58) | CSF1RKCNH2PDE4A | |
| SCHEMBL28527136 | 0.81 | CSF1R (0.56) | CSF1R | |
| SCHEMBL28528686 | 0.81 | CSF1R (0.55) | CSF1RKCNH2PDE4APDE4BPDE4C | |
| SCHEMBL28526527 | 0.80 | NPSR1 (0.60) | CSF1R | |
| SCHEMBL28522950 | 0.80 | CSF1R (0.53) | CSF1R | |
| SCHEMBL11017743 | 0.77 | CSF1R (0.49) | CSF1RKCNH2PDE4A | |
| SCHEMBL3290606 | 0.76 | CSF1R (0.58) | CSF1RKCNH2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848613-A | Diaryl pyrimidopyridinone derivative and preparation method and application thereof | 山东大学 | 2020-10-30 | — | — | CN | claimed |
| CN-111848613-B | Diaryl pyrimidopyridinone derivative and preparation method and application thereof | 山东大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-111848613-A | Diaryl pyrimidopyridinone derivative and preparation method and application thereof | 山东大学 | 2020-10-30 | — | — | CN | disclosed |