Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.56 |
| ▸ | PRKDC | P78527 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 13/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28640314 | 0.82 | PIK3CA (0.52) | PIK3CAPIK3CDPIK3CBPIK3CGPRKDC | |
| SCHEMBL2879628 | 0.81 | BRD4 (0.50) | PIK3CAPIK3CDPIK3CBPIK3CGPRKDC | |
| SCHEMBL2880810 | 0.78 | METAP2 (0.47) | PIK3CAPIK3CDPIK3CBPIK3CGPRKDC | |
| SCHEMBL28924972 | 0.76 | PIK3CA (0.60) | PIK3CAPIK3CDPIK3CBPIK3CGPRKDC | |
| SCHEMBL15876525 | 0.72 | METAP2 (0.44) | PIK3CAPIK3CDPIK3CBPIK3CGPRKDC | |
| SCHEMBL561236 | 0.72 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CBPIK3CGPRKDC | |
| SCHEMBL2883090 | 0.71 | KCNH2 (0.55) | BRD4 | |
| SCHEMBL3435497 | 0.70 | METAP2 (0.46) | PIK3CAPIK3CDPIK3CBPIK3CGPRKDC | |
| SCHEMBL28640313 | 0.70 | PIK3CA (0.59) | PIK3CAPIK3CDPIK3CBPIK3CGPRKDC | |
| SCHEMBL3435046 | 0.68 | BRD4 (0.56) | PIK3CABRD4METAP2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106659765-B | Use of dianhydrogalactitol and analogs or derivatives thereof for treating non-small cell lung cancer and ovarian cancer | 德玛医药 | 2021-08-13 | — | — | CN | disclosed |