Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of 1-Methylimidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.75 |
| ▸ | QPCT | Q16769 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.75 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Methylimidazole SCHEMBL29039597 | 0.97 | NFKB1 (0.79) | NFKB1QPCTHSD17B10QPCTLTBXAS1 | |
| 1-Methylimidazole SCHEMBL9991919 | 0.97 | NFKB1 (0.79) | NFKB1QPCTHSD17B10QPCTLTBXAS1 | |
| 1-Methylimidazole SCHEMBL28234698 | 0.95 | NFKB1 (0.75) | NFKB1QPCTHSD17B10QPCTLTBXAS1 | |
| 1-Methylimidazole SCHEMBL28202364 | 0.95 | NFKB1 (0.75) | NFKB1QPCTHSD17B10QPCTLTBXAS1 | |
| 1-Methylimidazole SCHEMBL27652184 | 0.95 | NFKB1 (0.75) | NFKB1QPCTHSD17B10QPCTLTBXAS1 | |
| 1-Methylimidazole SCHEMBL27649393 | 0.89 | NFKB1 (0.65) | NFKB1QPCTHSD17B10QPCTLTBXAS1 | |
| 1-Methylimidazole SCHEMBL28053535 | 0.87 | — | — | |
| 1-Methylimidazole SCHEMBL20112 | 0.87 | — | — | |
| 1-Methylimidazole SCHEMBL9244221 | 0.87 | NFKB1 (1.00) | NFKB1QPCTHSD17B10QPCTLTBXAS1 | |
| 1-Methylimidazole SCHEMBL4954973 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115584287-B | Naphthalene dispersant for preparing nano hydrocarbon fuel and application thereof | 神华准能资源综合开发有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-115584287-A | Naphthalene dispersant for preparing nano hydrocarbon fuel and application thereof | 神华准能资源综合开发有限公司 | 2023-01-10 | — | — | CN | claimed |
| CN-115584287-B | Naphthalene dispersant for preparing nano hydrocarbon fuel and application thereof | 神华准能资源综合开发有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-115584287-A | Naphthalene dispersant for preparing nano hydrocarbon fuel and application thereof | 神华准能资源综合开发有限公司 | 2023-01-10 | — | — | CN | disclosed |