SCHEMBL2893375

SCHEMBL2893375

CCC(N)NCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.52
IDO1 P14902 2/20 0.46
CYP3A4 P08684 2/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.44
SLC6A2 P23975 2/20 0.43
TAAR1 Q96RJ0 2/20 0.43
MAOA P21397 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
CYP2A6 P11509 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
THRB P10828 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
EPHX1 P07099 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11560509 0.98 SIGMAR1 (0.50) SIGMAR1IDO1CYP3A4MAPTKDM4E
SCHEMBL10937741 0.83 SIGMAR1 (0.44) SIGMAR1IDO1CYP3A4MAPTKDM4E
SCHEMBL10938990 0.83 SIGMAR1 (0.49) SIGMAR1IDO1CYP3A4MAPTKDM4E
SCHEMBL18032935 0.81 SIGMAR1 (0.59) SIGMAR1IDO1CYP3A4MAPTSLC6A2
SCHEMBL10939197 0.80 SIGMAR1 (0.55) SIGMAR1IDO1CYP3A4MAPTPOLB
SCHEMBL11121454 0.80 TLR2 (0.50) SIGMAR1
SCHEMBL10938232 0.79 SIGMAR1 (0.41) SIGMAR1IDO1CYP3A4MAPTKDM4E
SCHEMBL16268587 0.79 SIGMAR1 (0.47) SIGMAR1IDO1CYP3A4MAPTKDM4E
SCHEMBL9063683 0.78 SIGMAR1 (0.55) SIGMAR1IDO1CYP3A4MAPTKDM4E
SCHEMBL22207039 0.78 SIGMAR1 (0.55) SIGMAR1IDO1CYP3A4MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040082486-A1 Molybdenum-containing lubricant additive compositions and processes for making and using same ETHYL CORPORATION 2004-04-29 US claimed
US-6645921-B2 Reaction product of fatty oil, diamine, and molybdenum source; free of organic solvents, carbon disulfide, sulfur and phosphorus compounds; internal combustion engines for automobiles and trucks ETHYL CORPORATION 2003-11-11 US claimed
US-20030171226-A1 Molybdenum-containing lubricant additive compositions, and processes for making and using same ETHYL CORPORATION 2003-09-11 US claimed
CN-112218849-B Process for the preparation of amines 巴斯夫欧洲公司 2023-08-18 CN disclosed
US-11390578-B2 Method for synthesizing amines BASF SE (DE) 2022-07-19 US disclosed
EP-3774716-B1 PROCESS FOR THE PREPARATION OF AMINES BASF SE (DE) 2022-03-16 EP disclosed
US-20210155574-A1 METHOD FOR SYNTHESIZING AMINES BASF SE (DE) 2021-05-27 US disclosed
EP-3774716-A1 METHOD FOR SYNTHESIZING AMINES BASF SE (DE) 2021-02-17 EP disclosed
CN-112218849-A Process for preparing amines 巴斯夫欧洲公司 2021-01-12 CN disclosed
WO-2019192903-A1 METHOD FOR SYNTHESIZING AMINES BASF SE (DE) 2019-10-10 WO disclosed
EP-2782921-B1 ORGANIC TUNGSTEN COMPLEXES VANDERBILT CHEMICALS LLC (US) 2018-05-02 EP disclosed
WO-2006021457-A2 PYRIMIDINE DERIVATIVES NOVARTIS AG (CH) 2006-03-02 WO disclosed
US-6914037-B2 Molybdenum-containing lubricant additive compositions and processes for making and using same ETHYL CORPORATION (US) 2005-07-05 US disclosed
US-20040082486-A1 Molybdenum-containing lubricant additive compositions and processes for making and using same ETHYL CORPORATION 2004-04-29 US disclosed
US-6645921-B2 Reaction product of fatty oil, diamine, and molybdenum source; free of organic solvents, carbon disulfide, sulfur and phosphorus compounds; internal combustion engines for automobiles and trucks ETHYL CORPORATION 2003-11-11 US disclosed
US-20030171226-A1 Molybdenum-containing lubricant additive compositions, and processes for making and using same ETHYL CORPORATION 2003-09-11 US disclosed
EP-1338642-A1 Molybdenum-containing lubricant additive compositions, and processes for making the same ETHYL CORPORATION (US) 2003-08-27 EP disclosed
US-5070159-A DISPERSANTS FOR PIGMENTS HOECHST AKTIENGESELLSCHAFT (DE) 1991-12-03 US disclosed
US-4500452-A NOT SUBJECT TO ENZYME DEACTIVATION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1985-02-19 US disclosed
US-4472304-A CARCINOSTATIC NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1984-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11390578-B2 Method for synthesizing amines PNMT, ADH1A, ADH1C SIGMAR1 1209/4885IDO1 212/4885CYP3A4 379/4885
US-20040082486-A1 Molybdenum-containing lubricant additive compositions and processes for making and using same NOTUM, ALOX5, PHOSPHO1 SIGMAR1 483/4885IDO1 1528/4885CYP3A4 1002/4885
US-20210155574-A1 METHOD FOR SYNTHESIZING AMINES PNMT, ADH1A, ADH1C SIGMAR1 1209/4885IDO1 212/4885CYP3A4 379/4885
US-20030171226-A1 Molybdenum-containing lubricant additive compositions, and processes for making and using same NOTUM, AMD1, FDFT1 SIGMAR1 497/4885IDO1 1457/4885CYP3A4 1275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.