Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GALR2 | O43603 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28946153 | 0.83 | MAPT (0.44) | LMNAGALR2POLBTXNRD1VCAM1 | |
| SCHEMBL28946177 | 0.83 | PGK1 (0.46) | LMNAPOLBTXNRD1SMN1; SMN2VCAM1 | |
| SCHEMBL28964122 | 0.81 | L3MBTL1 (0.44) | LMNAPOLBTXNRD1SMN1; SMN2MAPT | |
| SCHEMBL28946179 | 0.81 | MAPT (0.39) | TXNRD1MAPTALDH1A1GLAGAA | |
| SCHEMBL28946165 | 0.79 | L3MBTL1 (0.54) | LMNAPOLBTXNRD1SMN1; SMN2MAPT | |
| SCHEMBL28946163 | 0.79 | TXNRD1 (0.42) | TXNRD1VCAM1MAPTALDH1A1RAB9A | |
| SCHEMBL3143317 | 0.78 | CYP3A4 (0.40) | LMNATXNRD1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL28946156 | 0.78 | MAPT (0.50) | LMNASMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL28946161 | 0.78 | LMNA (0.48) | LMNAPOLBTXNRD1MAPTALDH1A1 | |
| SCHEMBL28306174 | 0.77 | ALDH1A1 (0.47) | POLBSMN1; SMN2MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970633-B | Pyridine sulfone and derivative, preparation method and application thereof | 湖南化工研究院有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-109970633-B | Pyridine sulfone and derivative, preparation method and application thereof | 湖南化工研究院有限公司 | 2022-12-27 | — | — | CN | disclosed |