SCHEMBL28948259

SCHEMBL28948259

O=[N+]([O-])C1CCCCC1(O)OCc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.34
KDM4E B2RXH2 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 3/20 0.34
MEN1 O00255 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
FKBP1A P62942 2/20 0.34
SGMS2 Q8NHU3 1/20 0.33
TMEM97 Q5BJF2 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27896472 0.77 TRPA1 (0.38) KMT2AKDM4ESMN1; SMN2ALDH1A1MEN1
SCHEMBL5353805 0.76 TRPA1 (0.38) KMT2AKDM4ESMN1; SMN2ALDH1A1MEN1
SCHEMBL27847679 0.73 MAOA (0.36) KDM4ESMN1; SMN2ALDH1A1POLB
SCHEMBL2502222 0.73 NR5A2 (0.37)
SCHEMBL2204407 0.70 ALDH1A1 (0.36) KMT2AKDM4ESMN1; SMN2ALDH1A1MEN1
SCHEMBL15465575 0.69 CTSV (0.36) CYP3A4
SCHEMBL15465574 0.69 CTSV (0.36) CYP3A4
SCHEMBL21638945 0.68 TSHR (0.43) KMT2AALDH1A1MEN1CYP2C9CYP2C19
SCHEMBL6345843 0.68 PGR (0.38) KMT2AALDH1A1MEN1POLB
SCHEMBL28221758 0.68 GAA (0.46) KMT2ASMN1; SMN2ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677714-B Intermediate in preparation of (+) -water podocarpine and application thereof 昆明医科大学 2024-06-11 CN disclosed
CN-115894507-B Synthesis method and application of (+) -water podocarpine 昆明医科大学 2024-06-07 CN disclosed
CN-115894507-A Method for synthesizing (+) -canna oensis alkali and application thereof 昆明医科大学 2023-04-04 CN disclosed
CN-115677714-A Intermediate in preparation of (+) -coprinus comatus alkali and application thereof 昆明医科大学 2023-02-03 CN disclosed