Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 12/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 5/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19683931 | 0.95 | SIRT2 (0.37) | SIRT2SIRT1SIRT3SIRT5FAP | |
| SCHEMBL22698603 | 0.93 | SIRT2 (0.35) | SIRT2SIRT1SIRT3SIRT5FAP | |
| SCHEMBL20830828 | 0.92 | SIRT2 (0.34) | SIRT2SIRT1SIRT3SIRT5FAP | |
| SCHEMBL16847844 | 0.90 | OPRM1 (0.33) | SIRT2SIRT1SIRT3FAP | |
| SCHEMBL17801960 | 0.90 | ITGB1 (0.34) | SIRT2SIRT1SIRT3SIRT5FAP | |
| SCHEMBL17813693 | 0.89 | RAB9A (0.36) | SIRT2SIRT1SIRT3FAP | |
| SCHEMBL17650868 | 0.88 | HDAC3 (0.32) | SIRT2SIRT1FAP | |
| SCHEMBL21695294 | 0.88 | HDAC3 (0.37) | SIRT2SIRT1FAP | |
| SCHEMBL19803950 | 0.87 | HTR2A (0.37) | SIRT2SIRT1SIRT3SIRT5FAP | |
| SCHEMBL16847982 | 0.87 | HTR2A (0.37) | SIRT2SIRT1SIRT3SIRT5FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476648-B | Sevelamer antibody-drug conjugates and methods of use | 豪夫迈·罗氏有限公司 | 2022-09-13 | — | — | CN | disclosed |