Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 5/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958702 | 0.85 | HPGD (0.71) | HPGDALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL6077802 | 0.75 | L3MBTL1 (0.77) | ALDH1A1LMNAPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL6355362 | 0.75 | POLB (0.72) | LMNAPOLBTP53SMN1; SMN2L3MBTL1 | |
| SCHEMBL7159563 | 0.74 | ALDH1A1 (1.00) | HPGDALDH1A1LMNAMAPTTHRB | |
| SCHEMBL6362752 | 0.74 | KMT2A (0.60) | HPGDALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL13568183 | 0.74 | L3MBTL1 (0.60) | LMNATDP1POLBTP53SMN1; SMN2 | |
| SCHEMBL20804634 | 0.74 | L3MBTL1 (0.70) | ALDH1A1LMNASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL18320105 | 0.73 | LMNA (0.61) | HPGDALDH1A1LMNAPOLBTP53 | |
| SCHEMBL5261794 | 0.73 | MAPT (0.53) | HPGDALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL6356258 | 0.73 | PYGL (0.66) | HPGDALDH1A1LMNAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115707699-A | Anti-osteoporosis compound and application thereof | 中国医学科学院医药生物技术研究所 | 2023-02-21 | — | — | CN | disclosed |