Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.75 |
| ▸ | GLA | P06280 | 1/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.54 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.54 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.54 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MLYCD | O95822 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958730 | 0.96 | NPC1 (0.74) | HPGDGLAL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL28958700 | 0.90 | ALDH1A1 (0.73) | HPGDGLAL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL28958702 | 0.80 | HPGD (0.71) | HPGDALDH1A1POLBRAB9AMAPT | |
| SCHEMBL30865543 | 0.78 | NPC1 (0.79) | HPGDGLAL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL28958744 | 0.78 | MAPT (0.61) | HPGDALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL30954338 | 0.77 | L3MBTL1 (0.71) | HPGDGLAL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL11176654 | 0.77 | NPC1 (0.90) | HPGDNPC1POLBRAB9AHSP90AA1 | |
| SCHEMBL22546922 | 0.75 | HPGD (0.53) | HPGDGLAL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL8115111 | 0.75 | NPC1 (0.87) | NPC1POLBRAB9AHSP90AA1SMN1; SMN2 | |
| SCHEMBL6323713 | 0.75 | CA1 (0.51) | HPGDGLAL3MBTL1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115707699-A | Anti-osteoporosis compound and application thereof | 中国医学科学院医药生物技术研究所 | 2023-02-21 | — | — | CN | disclosed |