Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.74 |
| ▸ | HPGD | P15428 | 7/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958706 | 0.96 | HPGD (0.75) | NPC1HPGDALDH1A1L3MBTL1GLA | |
| SCHEMBL28958700 | 0.91 | ALDH1A1 (0.73) | NPC1HPGDALDH1A1L3MBTL1GLA | |
| SCHEMBL28958702 | 0.81 | HPGD (0.71) | HPGDALDH1A1RAB9AMAPTPOLB | |
| SCHEMBL30865543 | 0.79 | NPC1 (0.79) | NPC1HPGDALDH1A1L3MBTL1GLA | |
| SCHEMBL28958744 | 0.79 | MAPT (0.61) | NPC1HPGDALDH1A1RAB9AMAPT | |
| SCHEMBL30954338 | 0.78 | L3MBTL1 (0.71) | NPC1HPGDALDH1A1L3MBTL1GLA | |
| SCHEMBL22546922 | 0.77 | HPGD (0.53) | NPC1HPGDALDH1A1L3MBTL1GLA | |
| SCHEMBL3225126 | 0.76 | NPC1 (1.00) | NPC1HPGDALDH1A1L3MBTL1RAB9A | |
| SCHEMBL31337274 | 0.76 | HPGD (1.00) | NPC1HPGDALDH1A1L3MBTL1GLA | |
| SCHEMBL17510994 | 0.75 | HIF1A (0.67) | NPC1ALDH1A1RAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115707699-A | Anti-osteoporosis compound and application thereof | 中国医学科学院医药生物技术研究所 | 2023-02-21 | — | — | CN | disclosed |