Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | HPGD | P15428 | 5/20 | 0.73 |
| ▸ | NPC1 | O15118 | 5/20 | 0.73 |
| ▸ | RAB9A | P51151 | 4/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958730 | 0.91 | NPC1 (0.74) | ALDH1A1HPGDNPC1RAB9AMAPT | |
| SCHEMBL28958706 | 0.90 | HPGD (0.75) | ALDH1A1HPGDNPC1RAB9AMAPT | |
| SCHEMBL30865543 | 0.89 | NPC1 (0.79) | ALDH1A1HPGDNPC1RAB9AMAPT | |
| SCHEMBL28958744 | 0.88 | MAPT (0.61) | ALDH1A1HPGDNPC1RAB9AMAPT | |
| SCHEMBL31337274 | 0.84 | HPGD (1.00) | ALDH1A1HPGDNPC1RAB9AMAPT | |
| SCHEMBL28958702 | 0.84 | HPGD (0.71) | ALDH1A1HPGDRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL30954338 | 0.81 | L3MBTL1 (0.71) | ALDH1A1HPGDNPC1RAB9AMAPT | |
| SCHEMBL7155752 | 0.77 | ALDH1A1 (0.76) | ALDH1A1HPGDNPC1RAB9AMAPT | |
| SCHEMBL6428395 | 0.77 | CASP6 (0.68) | ALDH1A1HPGDNPC1RAB9AMAPT | |
| SCHEMBL31337267 | 0.76 | ALDH1A1 (0.74) | ALDH1A1HPGDNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115707699-A | Anti-osteoporosis compound and application thereof | 中国医学科学院医药生物技术研究所 | 2023-02-21 | — | — | CN | disclosed |