Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | F13A1 | P00488 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ESRRB | O95718 | 3/20 | 0.51 |
| ▸ | ESRRG | P62508 | 3/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958700 | 0.88 | ALDH1A1 (0.73) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28958730 | 0.79 | NPC1 (0.74) | MAPTNPC1RAB9ACYP1A2GAA | |
| SCHEMBL28958706 | 0.78 | HPGD (0.75) | MAPTNPC1RAB9AGFERSMN1; SMN2 | |
| SCHEMBL30954338 | 0.78 | L3MBTL1 (0.71) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7155752 | 0.77 | ALDH1A1 (0.76) | MAPTNPC1RAB9ACYP1A2GAA | |
| SCHEMBL31420450 | 0.76 | NPC1 (0.84) | MAPTNPC1RAB9ACYP1A2GAA | |
| SCHEMBL8668493 | 0.76 | NPC1 (1.00) | MAPTNPC1RAB9ACYP1A2GAA | |
| SCHEMBL1368482 | 0.76 | NPC1 (1.00) | MAPTNPC1RAB9ACYP1A2GAA | |
| SCHEMBL30865543 | 0.75 | NPC1 (0.79) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2191045 | 0.73 | KDM4E (0.65) | MAPTNPC1RAB9ACYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115707699-A | Anti-osteoporosis compound and application thereof | 中国医学科学院医药生物技术研究所 | 2023-02-21 | — | — | CN | disclosed |