Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 1/20 | 0.46 |
| ▸ | HEXB | P07686 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16196251 | 0.79 | USP7 (0.42) | HEXAHEXBRAB9AL3MBTL1MEN1 | |
| SCHEMBL2936454 | 0.76 | CNR2 (0.51) | HEXAHEXBRAB9ACNR1CNR2 | |
| SCHEMBL11901043 | 0.73 | MAP4K4 (0.48) | HEXAHEXBRAB9AMAP4K4KMO | |
| SCHEMBL18263138 | 0.72 | MAP4K4 (0.53) | RAB9AMAP4K4ADORA1FYNACVR1 | |
| SCHEMBL4582784 | 0.71 | MAP4K4 (0.69) | HEXAHEXBRAB9AMAP4K4MEN1 | |
| SCHEMBL6658640 | 0.70 | CNR2 (0.49) | HEXAHEXBRAB9ACNR1CNR2 | |
| SCHEMBL11821346 | 0.70 | KMO (0.51) | RAB9ACNR2MAP4K4KMOKMT2A | |
| SCHEMBL11158123 | 0.70 | RAB9A (0.43) | RAB9AMAP4K4KMOKDRPLK1 | |
| SCHEMBL6930975 | 0.69 | RAB9A (0.52) | HEXAHEXBRAB9ACNR1CNR2 | |
| SCHEMBL3869774 | 0.69 | RAB9A (0.52) | HEXAHEXBRAB9ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585128-B | Pyrazole derivatives as MALT1 inhibitors | 詹森药业有限公司 | 2023-02-21 | — | — | CN | disclosed |