Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | LTK | P29376 | 1/20 | 0.48 |
| ▸ | GRK5 | P34947 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582784 | 0.81 | MAP4K4 (0.69) | MAP4K4KDRADORA1LRRK2CHEK1 | |
| SCHEMBL12100759 | 0.81 | MAP4K4 (0.46) | MAP4K4PRKACAGSK3BMAP2K1NOS3 | |
| SCHEMBL17555726 | 0.79 | FYN (0.49) | MAP4K4FYNPIM1PRKACAGSK3B | |
| SCHEMBL23319557 | 0.79 | MAP4K4 (0.45) | MAP4K4ADORA1RAB9ANOS3NOS2 | |
| SCHEMBL11902083 | 0.79 | MAP4K4 (0.56) | MAP4K4KDRADORA1LRRK2ABL1 | |
| SCHEMBL4938505 | 0.79 | DYRK1A (0.54) | MAP4K4ADORA1LRRK2ABL1FYN | |
| SCHEMBL11158123 | 0.79 | RAB9A (0.43) | MAP4K4KDRADORA1LRRK2CHEK1 | |
| SCHEMBL11821346 | 0.79 | KMO (0.51) | MAP4K4KDRADORA1LRRK2CHEK1 | |
| SCHEMBL13730604 | 0.78 | NOS3 (0.52) | MAP4K4KDRLRRK2GSK3BAURKB | |
| SCHEMBL1165179 | 0.77 | GSK3B (0.47) | MAP4K4KDRADORA1LRRK2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11600791-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-03-07 | — | — | US | disclosed |
| EP-3936512-A1 | PYRIDYL CARBENE PHOSPHORESCENT EMITTERS | Universal Display Corporation (US) | 2022-01-12 | — | — | EP | disclosed |
| EP-3424935-B1 | IMIDAZOPYRAZINYL CARBENE PHOSPHORESCENT EMITTERS | UNIVERSAL DISPLAY CORP (US) | 2021-08-11 | — | — | EP | disclosed |
| US-20210050530-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2021-02-18 | — | — | US | disclosed |
| US-10873038-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-12-22 | — | — | US | disclosed |
| US-20190109287-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2019-04-11 | — | — | US | disclosed |
| EP-3424935-A1 | PYRIDYL CARBENE PHOSPHORESCENT EMITTERS | Universal Display Corporation (US) | 2019-01-09 | — | — | EP | disclosed |
| EP-2683728-B1 | IRIDIUM COMPLEXES WITH 3-PHENYL-3H-IMIDAZO[4,5-b]PYRIDINE, 3-PHENYL-3H-IMIDAZO[4,5-b]PYRAZINE AND 1-PHENYL-3H-IMIDAZO[4,5-b]PYRIDINE CARBENE LIGANDS USED AS PHOSPHORESCENT EMITTERS IN ORGANIC LIGHT EMITTING DEVICES | UNIVERSAL DISPLAY CORP (US) | 2018-09-05 | — | — | EP | disclosed |
| US-9972793-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-05-15 | — | — | US | disclosed |
| CN-103476767-B | Heterocyclic compounds as PI3 kinase inhibitors | HOFFMANN LA ROCHE | 2015-06-10 | — | — | CN | disclosed |
| US-20150021590-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2015-01-22 | — | — | US | disclosed |
| US-8883322-B2 | Pyridyl carbene phosphorescent emitters | UNIVERSAL DISPLAY CORPORATION (US) | 2014-11-11 | — | — | US | disclosed |
| US-8653089-B2 | Heterocyclic compounds and methods of use | F. HOFFMANN-LA ROCHE AG (CH) | 2014-02-18 | — | — | US | disclosed |
| EP-2683728-A2 | PYRIDYL CARBENE PHOSPHORESCENT EMITTERS | Universal Display Corporation (US) | 2014-01-15 | — | — | EP | disclosed |
| EP-2673269-A1 | HETEROCYCLIC COMPOUNDS AS PI3 KINASE INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-12-18 | — | — | EP | disclosed |
| US-20120228583-A1 | PYRIDYL CARBENE PHOSPHORESCENT EMITTERS | UNIVERSAL DISPLAY CORPORATION (US) | 2012-09-13 | — | — | US | disclosed |
| WO-2012121936-A2 | PYRIDYL CARBENE PHOSPHORESCENT EMITTERS | UNIVERSAL DISPLAY CORPORATION (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012107465-A1 | HETEROCYCLIC COMPOUNDS AS PI3 KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-08-16 | — | — | WO | disclosed |
| US-20120202785-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210050530-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | NUDC, NCL, NDC1 | MAP4K4 2876/4885KDR 1040/4885ADORA1 3679/4885 |
| US-10873038-B2 | Organic electroluminescent materials and devices | NUDC, NCL, NDC1 | MAP4K4 2876/4885KDR 1040/4885ADORA1 3679/4885 |
| US-20120202785-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | PIK3CA, PIK3CD, AKT3 | MAP4K4 191/4885KDR 1959/4885ADORA1 2558/4885 |
| US-20120228583-A1 | PYRIDYL CARBENE PHOSPHORESCENT EMITTERS | PAICS, PIR, NUDC | MAP4K4 2758/4885KDR 835/4885ADORA1 2146/4885 |
| US-20190109287-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | NUDC, NCL, NDC1 | MAP4K4 2876/4885KDR 1040/4885ADORA1 3679/4885 |
| US-11600791-B2 | Organic electroluminescent materials and devices | NUDC, NCL, NDC1 | MAP4K4 2876/4885KDR 1040/4885ADORA1 3679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.