Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10825752 | 0.75 | ALDH1A1 (0.43) | HDAC1HDAC6HDAC8ALDH1A1PKM | |
| SCHEMBL8809884 | 0.74 | HRH3 (0.68) | HDAC1KDM4EALDH1A1PKMHRH3 | |
| SCHEMBL10789534 | 0.73 | HRH3 (0.71) | HDAC1KDM4EALDH1A1PKMHRH3 | |
| SCHEMBL294763 | 0.73 | HRH3 (0.71) | HDAC1KDM4EALDH1A1PKMHRH3 | |
| SCHEMBL1847296 | 0.73 | HRH3 (0.71) | HDAC1KDM4EALDH1A1PKMHRH3 | |
| SCHEMBL24574127 | 0.73 | HRH3 (0.71) | HDAC1KDM4EALDH1A1PKMHRH3 | |
| SCHEMBL28965124 | 0.73 | DRD2 (0.44) | DRD2DRD4DRD3HDAC1ALDH1A1 | |
| SCHEMBL28958743 | 0.73 | PDE10A (0.45) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL15104529 | 0.72 | DRD2 (0.43) | DRD2DRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL8808928 | 0.72 | GFER (0.56) | DRD2DRD4DRD3ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264901-B | Amino phenol oxygroup zinc complex containing 2-substituted thiazole-4-group and preparation method and application thereof | 华东理工大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-113264901-A | Amino phenol oxygroup zinc complex containing 2-substituted thiazole-4-group and preparation method and application thereof | 华东理工大学 | 2021-08-17 | — | — | CN | disclosed |