SCHEMBL289656

SCHEMBL289656

CC(=O)c1cccc(OBOc2cccc(C(C)=O)c2)c1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
MAOB P27338 12/20 0.56
NPC1 O15118 1/20 0.53
ALDH1A1 P00352 1/20 0.53
RAB9A P51151 1/20 0.53
MAOA P21397 4/20 0.51
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
CYP1A2 P05177 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
MAPK1 P28482 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PARP1 P09874 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL799040 0.86 KMT2A (0.56) KMT2AMEN1MAOBNPC1ALDH1A1
SCHEMBL132082 0.84 AKR1C3 (0.63) KMT2ANPC1RAB9A
SCHEMBL25620248 0.83 MEN1 (0.71) KMT2AMEN1MAOBNPC1ALDH1A1
SCHEMBL177641 0.83 SMN1; SMN2 (0.55) KMT2AMEN1NPC1ALDH1A1RAB9A
SCHEMBL191052 0.82 PARP1 (0.65) KMT2AMEN1CES2CES1L3MBTL1
SCHEMBL177413 0.82 F10 (0.48) KMT2AMEN1MAOBALDH1A1MAOA
SCHEMBL190231 0.82 HDAC8 (0.56) KMT2AMEN1NPC1ALDH1A1RAB9A
SCHEMBL52445 0.82 CES2 (0.74) KMT2AMEN1MAOBNPC1ALDH1A1
SCHEMBL28126653 0.82 CES2 (0.74) KMT2AMEN1MAOBNPC1ALDH1A1
SCHEMBL29589944 0.82 CES2 (0.74) KMT2AMEN1MAOBNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11876137-B2 Field-effect transistor including a metal oxide composite protective layer, and display element, image display device, and system including the field-effect transistor RICOH COMPANY, LTD. (JP) 2024-01-16 US claimed
US-20200083383-A1 FIELD-EFFECT TRANSISTOR INCLUDING A METAL OXIDE COMPOSITE PROTECTIVE LAYER, AND DISPLAY ELEMENT, IMAGE DISPLAY DEVICE, AND SYSTEM INCLUDING THE FIELD-EFFECT TRANSISTOR RICOH COMPANY, LTD. (JP) 2020-03-12 US claimed
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-05-21 US disclosed
EP-4262788-B1 UREA OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME LLC (US) 2026-01-21 EP disclosed
US-20250257049-A1 HETEROCYCLIC COMPOUNDS AS MODULATORS OF MGLUR7 PRAGMA THERAPEUTICS (FR) 2025-08-14 US disclosed
CN-111148744-B Novel heterocyclic compounds as MGLUR7 modulators 布拉格玛治疗公司 2025-02-14 CN disclosed
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2025-01-02 US disclosed
CN-113645971-B Compounds and uses thereof 福宏治疗公司 2024-10-18 CN disclosed
US-20240293559-A1 SHP2 inhibitor, pharmaceutical composition containing the same and application thereof BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) 2024-09-05 US disclosed
US-12071445-B2 Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same YALE UNIVERSITY (US) 2024-08-27 US disclosed
EP-4417600-A1 SHP2 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF Beijing Tide Pharmaceutical Co., Ltd. (CN) 2024-08-21 EP disclosed
WO-2003048164-A2 ADENOSINE A2A RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2003-06-12 WO disclosed
EP-1283209-A1 NOVEL BENZOTHIOPHENE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2003-02-12 EP disclosed
WO-2002098848-A1 BENZOYLSULFONAMIDES AND SULFONYLBENZAMIDINES FOR USE AS ANTITUMOUR AGENTS ELI LILLY AND COMPANY (US) 2002-12-12 WO disclosed
WO-2002057273-A9 SERINE PROTEASE INHIBITORS COMPRISING A HYDROGEN-BOND ACCEPTOR TRIGEN LTD (GB) 2002-11-28 WO disclosed
US-20020156295-A1 Ligands for metals and improved metal-catalyzed processes based thereon NATIONAL SCIENCE FOUNDATION 2002-10-24 US disclosed
WO-2002057273-A1 SERINE PROTEASE INHIBITORS COMPRISING A HYDROGEN-BOND ACCEPTOR TRIGEN LIMITED (GB) 2002-07-25 WO disclosed
US-6307087-B1 USE OF CATALYSTS COMPRISING THESE LIGANDS IN TRANSITION METAL-CATALYZED CARBON-HETEROATOM AND CARBON-CARBON BOND-FORMING REACTIONS. MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2001-10-23 US disclosed
EP-1097158-A2 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2001-05-09 EP disclosed
WO-2000002887-A2 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2000-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME TIMCC, YAP1, TET2 KMT2A 1431/4885MEN1 938/4885MAOB 3234/4885
US-20250257049-A1 HETEROCYCLIC COMPOUNDS AS MODULATORS OF MGLUR7 GRM7, GRM1, GRM2 KMT2A 2063/4885MEN1 4455/4885MAOB 2490/4885
US-20240293559-A1 SHP2 inhibitor, pharmaceutical composition containing the same and application thereof PTPN1, PTPN5, PTPN18 KMT2A 2047/4885MEN1 1603/4885MAOB 3531/4885
US-20020156295-A1 Ligands for metals and improved metal-catalyzed processes based thereon THEM6, SOD1, SLC30A6 KMT2A 2881/4885MEN1 1595/4885MAOB 967/4885
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF FSHR, GNRHR, LHCGR KMT2A 1938/4885MEN1 688/4885MAOB 2905/4885
US-12071445-B2 Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same TIMCC, YAP1, TET2 KMT2A 1597/4885MEN1 781/4885MAOB 3035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.