SCHEMBL177641

SCHEMBL177641

COC(=O)c1cccc(OBOc2cccc(C(=O)OC)c2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.55
TP53 P04637 2/20 0.55
CYP4F2 P78329 2/20 0.54
CYP4A11 Q02928 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.52
TSHR P16473 1/20 0.52
LOXL2 Q9Y4K0 1/20 0.51
RAB9A P51151 5/20 0.51
NPC1 O15118 4/20 0.51
ALDH1A1 P00352 2/20 0.51
MEN1 O00255 1/20 0.51
PKM P14618 1/20 0.51
HPGD P15428 1/20 0.51
MAPK1 P28482 1/20 0.51
KMT2A Q03164 1/20 0.51
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
PRSS1 P07477 1/20 0.49
ACR P10323 1/20 0.49
POLB P06746 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11946638 0.88 SMN1; SMN2 (0.54) SMN1; SMN2TP53CYP4F2CYP4A11L3MBTL1
Methyl 3-Methoxybenzoate SCHEMBL29702092 0.83 SMN1; SMN2 (0.73) SMN1; SMN2TP53TSHRRAB9ANPC1
Methyl 3-Methoxybenzoate SCHEMBL384913 0.83 SMN1; SMN2 (0.73) SMN1; SMN2TP53TSHRRAB9ANPC1
SCHEMBL289656 0.83 KMT2A (0.57) SMN1; SMN2L3MBTL1RAB9ANPC1ALDH1A1
SCHEMBL2436534 0.83 L3MBTL1 (0.65) SMN1; SMN2TP53CYP4F2CYP4A11L3MBTL1
SCHEMBL521172 0.81 SLC7A5 (0.48) SMN1; SMN2TP53CYP4F2CYP4A11L3MBTL1
SCHEMBL177281 0.81 SMN1; SMN2 (0.52) SMN1; SMN2TP53CYP4F2CYP4A11RAB9A
SCHEMBL527464 0.81 CYP4F2 (0.52) SMN1; SMN2TP53CYP4F2CYP4A11L3MBTL1
SCHEMBL190231 0.81 HDAC8 (0.56) SMN1; SMN2TP53TSHRRAB9ANPC1
SCHEMBL25620305 0.81 MEN1 (0.59) SMN1; SMN2TP53L3MBTL1TSHRLOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3478792-B1 CHEMILUMINESCENT SUBSTRATES BECKMAN COULTER INC (US) 2023-12-13 EP claimed
US-10703971-B2 Chemiluminescent substrates BECKMAN COULTER, INC. (US) 2020-07-07 US claimed
US-20190161675-A1 CHEMILUMINESCENT SUBSTRATES BECKMAN COULTER, INC. (US) 2019-05-30 US claimed
EP-3478792-A1 CHEMILUMINESCENT SUBSTRATES Beckman Coulter Inc. (US) 2019-05-08 EP claimed
WO-2018006059-A1 CHEMILUMINESCENT SUBSTRATES BECKMAN COULTER, INC. (US) 2018-01-04 WO claimed
US-20260078117-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMA INC (US) 2026-03-05 US disclosed
US-12545640-B2 Substituted 6,7-dihydro-5H-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof SANOFI (FR) 2026-02-10 US disclosed
US-20260016471-A1 IMPROVED ASSAY COMPOSITIONS AND METHODS BECKMAN COULTER INC (US) 2026-01-15 US disclosed
US-20250215012-A1 IKZF2 DEGRADERS AND USES THEREOF UNIV MICHIGAN (US) 2025-07-03 US disclosed
US-20250214969-A1 PROTEIN DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-07-03 US disclosed
US-20250115579-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2025-04-10 US disclosed
WO-2003059884-A1 MODULATORS OF LXR X-CEPTOR THERAPEUTICS, INC. (US) 2003-07-24 WO disclosed
EP-1313711-A2 INDAZOLE DERIVATIVES AS JNK INHIBITORS SIGNAL PHARMACEUTICALS, INC. (US) 2003-05-28 EP disclosed
WO-2003024949-A1 DNA-PK INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2003-03-27 WO disclosed
WO-2002010137-A9 INDAZOLE DERIVATIVES AS JNK INHIBITORS SIGNAL PHARM INC (US) 2003-02-06 WO disclosed
WO-2002096867-A2 INHIBITORS OF PROTEIN KINASE FOR THE TREATMENT OF DISEASE LG BIOMEDICAL INSTITUTE (US) 2002-12-05 WO disclosed
US-20020103229-A1 Indazole derivatives as JNK inhibitors and compositions and methods related thereto SIGNAL PHARMACEUTICALS, LLC 2002-08-01 US disclosed
WO-2002010137-A2 INDAZOLE DERIVATIVES AS JNK INHIBITORS SIGNAL PHARMACEUTICALS, INC. (US) 2002-02-07 WO disclosed
US-5455252-A Antiinflammatory agent, immunosuppressant, antiallergen, skin disorders, bronchodilator, analgesic SYNTEX (U.S.A.) INC. (US) 1995-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115579-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS CGAS, GLS2, GLS SMN1; SMN2 2633/4885TP53 503/4885CYP4F2 2014/4885
US-20260062443-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS C9, SSB, C1S SMN1; SMN2 21/4885TP53 4612/4885CYP4F2 3860/4885
US-20260016471-A1 IMPROVED ASSAY COMPOSITIONS AND METHODS ALPL, AGL, ALPP SMN1; SMN2 4616/4885TP53 729/4885CYP4F2 1401/4885
US-20250215012-A1 IKZF2 DEGRADERS AND USES THEREOF IKZF1, IKZF2, IKZF3 SMN1; SMN2 2807/4885TP53 62/4885CYP4F2 59/4885
US-12545640-B2 Substituted 6,7-dihydro-5H-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof ESRRA, GPER1, FSHR SMN1; SMN2 3663/4885TP53 1751/4885CYP4F2 196/4885
US-20250214969-A1 PROTEIN DEGRADERS AND USES THEREOF MDM2, CUL1, PSMG3 SMN1; SMN2 1231/4885TP53 242/4885CYP4F2 3600/4885
US-20020103229-A1 Indazole derivatives as JNK inhibitors and compositions and methods related thereto MAP3K7, MAP3K1, MAP3K8 SMN1; SMN2 4475/4885TP53 667/4885CYP4F2 2542/4885
US-20260078117-A1 COMPOUNDS AND METHODS OF USE NR3C2, ADRA1A, CNR1 SMN1; SMN2 1645/4885TP53 3467/4885CYP4F2 726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.