Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | RXRB | P28702 | 1/20 | 0.53 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 6/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28032601 | 0.90 | KMO (0.59) | RXRARXRBKAT6AKMOSERPINE1 | |
| SCHEMBL726544 | 0.88 | KMO (0.53) | RXRARXRBKMOHDAC8 | |
| SCHEMBL726087 | 0.88 | KMO (0.56) | RXRARXRBKMOHDAC8 | |
| SCHEMBL699008 | 0.86 | KMO (0.67) | RXRARXRBKAT6AKMOSERPINE1 | |
| SCHEMBL30698052 | 0.86 | KMO (0.67) | RXRARXRBKAT6AKMOSERPINE1 | |
| SCHEMBL307574 | 0.85 | RXRA (0.73) | RXRARXRBSUCNR1CNR1KAT6A | |
| Hydrogen Sulfide SCHEMBL27896825 | 0.84 | KMO (0.64) | RXRARXRBKAT6AKMOSERPINE1 | |
| SCHEMBL3723969 | 0.83 | PARP1 (0.63) | RXRARXRBSUCNR1CNR1KAT6A | |
| SCHEMBL244674 | 0.83 | DHODH (0.54) | RXRARXRBKMOUTS2RHDAC8 | |
| SCHEMBL207988 | 0.79 | AURKA (0.50) | RXRARXRBCNR1KMOHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819391-A | Baicalein derivative, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-03-21 | — | — | CN | disclosed |