Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167294 | 0.82 | MAPT (0.45) | MAPTHSD17B10TP53ALOX15GAA | |
| SCHEMBL135288 | 0.80 | AKR1C1 (0.35) | ALOX15KMT2ACHRM2CHRM1TSHR | |
| SCHEMBL7640011 | 0.78 | MAPT (0.47) | MAPTHSD17B10OPRD1OPRK1GAA | |
| SCHEMBL29216618 | 0.78 | PDCD1 (0.41) | MAPTHSD17B10TP53ALOX15OPRD1 | |
| Isopropylamine SCHEMBL28970090 | 0.78 | ALDH1A1 (0.34) | GAAKDM4EKMT2ACHRM2CHRM1 | |
| SCHEMBL28574647 | 0.77 | POLB (0.35) | MAPTHSD17B10KMT2ACHRM2CHRM1 | |
| SCHEMBL29498824 | 0.74 | LDHA (0.36) | KMT2ACHRM2CHRM1 | |
| SCHEMBL6051256 | 0.73 | LMNA (0.44) | MAPTHSD17B10GAAKDM4EKMT2A | |
| SCHEMBL342177 | 0.73 | MAPT (0.43) | MAPTHSD17B10TP53OPRD1GAA | |
| SCHEMBL1832298 | 0.72 | PTGDR2 (0.38) | GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806531-A | Preparation method of 4, 5-dihydro-5, 5-diphenyl isoxazole-3-formic acid and derivatives thereof | 新发药业有限公司 | 2023-03-17 | — | — | CN | disclosed |