SCHEMBL7167294

SCHEMBL7167294

COC(=O)C1=NOC(c2ccccc2)(c2ccccc2)C1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.45
HSD17B10 Q99714 3/20 0.45
KDM4E B2RXH2 3/20 0.43
GAA P10253 2/20 0.43
KMT2A Q03164 2/20 0.43
TSHR P16473 2/20 0.41
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.36
ALOX15 P16050 1/20 0.36
LMNA P02545 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ALDH1A1 P00352 2/20 0.35
PTGS1 P23219 1/20 0.35
HTT P42858 1/20 0.35
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7640011 0.84 MAPT (0.47) MAPTHSD17B10KDM4EGAAKMT2A
SCHEMBL124147 0.84 MAPT (0.47) MAPTHSD17B10KDM4EGAAKMT2A
SCHEMBL29216618 0.84 PDCD1 (0.41) MAPTHSD17B10KDM4EKMT2ATSHR
SCHEMBL31501104 0.82 MAPT (0.44) MAPTHSD17B10KDM4EGAAKMT2A
SCHEMBL31501105 0.82 MAPT (0.44) MAPTHSD17B10KDM4EGAAKMT2A
SCHEMBL135288 0.82 AKR1C1 (0.35) KMT2ATSHRMEN1ALOX15ALDH1A1
SCHEMBL28970097 0.82 MAPT (0.43) MAPTHSD17B10KDM4EGAAKMT2A
SCHEMBL28574647 0.80 POLB (0.35) MAPTHSD17B10KMT2ATSHRMEN1
SCHEMBL29498824 0.80 LDHA (0.36) KMT2AMEN1RAB9A
SCHEMBL6051256 0.79 LMNA (0.44) MAPTHSD17B10KDM4EGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404618-B2 Herbicidal composition SYNGENTA LIMITED (GB) 2013-03-26 US disclosed
US-20100048398-A1 HERBICIDAL COMBINATION SYNGENTA CROP PROTECTION, INC. (US) 2010-02-25 US disclosed
US-7579301-B2 Herbicidal compositions comprising benzoylpyrazoles and safeners BAYER CROPSCIENCE AG (DE) 2009-08-25 US disclosed
US-7579301-B2 Herbicidal compositions comprising benzoylpyrazoles and safeners BAYER CROPSCIENCE AG (DE) 2009-08-25 US disclosed
US-20070259786-A1 Herbicidal Composition SYNGENTA CROP PROTECTION, INC. (US) 2007-11-08 US disclosed
CN-1201658-C Herbicidal formulations AVENTIS CROPSCIENCE GMBH (DE) 2005-05-18 CN disclosed
US-6569805-B1 Synergistic mixture of certain phenylsulfonylureas and/or their salts and vegetable oils for controlling weeds in crops AVENTIS CROPSCIENCE GMBH (DE) 2003-05-27 US disclosed
CN-1391440-A Herbicidal formulations AVENTIS CROPSCIENCE GMBH (DE) 2003-01-15 CN disclosed
CN-1318978-A Herbicidal compositions containing substituted phenoxysulfonylureas AVENTIS CROPSCIENCE GMBH (DE) 2001-10-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070259786-A1 Herbicidal Composition DDT, IDH2, ACHE MAPT 3708/4885HSD17B10 178/4885KDM4E 1547/4885
US-20100048398-A1 HERBICIDAL COMBINATION PFAS, PGM2, GSTM2 MAPT 2798/4885HSD17B10 2177/4885KDM4E 4469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.