Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.81 |
| ▸ | POLB | P06746 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | NPC1 | O15118 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | RAB9A | P51151 | 2/20 | 0.81 |
| ▸ | GFER | P55789 | 2/20 | 0.81 |
| ▸ | GABRP | O00591 | 1/20 | 0.81 |
| ▸ | GABRD | O14764 | 1/20 | 0.81 |
| ▸ | PIM1 | P11309 | 1/20 | 0.81 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.81 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.81 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.81 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.81 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.81 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.81 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.81 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.81 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hispidulin SCHEMBL29458970 | 0.90 | POLB (1.00) | FLT3POLBMAPTMEN1NPC1 | |
| Hispidulin SCHEMBL514926 | 0.90 | POLB (1.00) | FLT3POLBMAPTMEN1NPC1 | |
| Pectolinarigenin SCHEMBL29606971 | 0.89 | MAPT (1.00) | FLT3POLBMAPTMEN1NPC1 | |
| Pectolinarigenin SCHEMBL243686 | 0.89 | MAPT (1.00) | FLT3POLBMAPTMEN1NPC1 | |
| SCHEMBL17258304 | 0.88 | FLT3 (0.81) | FLT3POLBMAPTMEN1NPC1 | |
| SCHEMBL28978248 | 0.88 | FLT3 (0.81) | FLT3POLBMAPTMEN1NPC1 | |
| SCHEMBL30288880 | 0.88 | FLT3 (0.81) | FLT3POLBMAPTMEN1NPC1 | |
| SCHEMBL737628 | 0.88 | FLT3 (0.81) | FLT3POLBMAPTMEN1NPC1 | |
| Oroxylin A SCHEMBL431423 | 0.87 | CREB1 (1.00) | FLT3POLBMAPTMEN1NPC1 | |
| Oroxylin A SCHEMBL30452350 | 0.87 | CREB1 (1.00) | FLT3POLBMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894422-A | PPAR gamma agonist and combination and application thereof | 上海中医药大学 | 2023-04-04 | — | — | CN | disclosed |