SCHEMBL28984612

SCHEMBL28984612

COc1cc(-c2cccc(C)c2)c(OC)c(OC)c1OC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.54
ALDH1A1 P00352 4/20 0.54
HSD17B10 Q99714 4/20 0.50
TSHR P16473 3/20 0.50
KDM4E B2RXH2 2/20 0.50
LMNA P02545 1/20 0.50
TUBB4A P04350 3/20 0.47
TUBB P07437 3/20 0.47
TUBA3C P0DPH7 3/20 0.47
TUBA1B P68363 3/20 0.47
TUBA4A P68366 3/20 0.47
TUBB4B P68371 3/20 0.47
TUBB3 Q13509 3/20 0.47
TUBB2A Q13885 3/20 0.47
TUBB8 Q3ZCM7 3/20 0.47
TUBA3E Q6PEY2 3/20 0.47
TUBA1A Q71U36 3/20 0.47
TUBA1C Q9BQE3 3/20 0.47
TUBB6 Q9BUF5 3/20 0.47
TUBB2B Q9BVA1 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL205626 0.82 PDE4B (0.50) HPGDALDH1A1KDM4ETUBB4ATUBB
SCHEMBL13811081 0.79 HPGD (0.50) HPGDALDH1A1HSD17B10TSHRKDM4E
SCHEMBL5541170 0.77 TP53 (0.61) HPGDALDH1A1HSD17B10ACHENPC1
SCHEMBL15906120 0.77 ACHE (0.52) HPGDALDH1A1HSD17B10TSHRKDM4E
SCHEMBL4602476 0.76 ERN1 (0.50) ALDH1A1LMNA
SCHEMBL22360334 0.75 TUBB4A (0.46) HPGDALDH1A1HSD17B10TSHRKDM4E
SCHEMBL27695762 0.75 HPGD (0.44) HPGDALDH1A1HSD17B10TSHRKDM4E
SCHEMBL20022114 0.74 ALDH1A1 (0.58) HPGDALDH1A1HSD17B10NPC1RAB9A
SCHEMBL20022116 0.74 ALDH1A1 (0.58) HPGDALDH1A1HSD17B10NPC1RAB9A
SCHEMBL13241161 0.74 ALDH1A1 (0.51) HPGDALDH1A1HSD17B10TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115959974-A Preparation method of 3,3', 5' -tetramethoxymethyl biphenyl diphenol 天津泰合利华材料科技有限公司 2023-04-14 CN disclosed