Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.35 |
| ▸ | ATIC | P31939 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 3/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | BRD1 | O95696 | 1/20 | 0.30 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339035 | 0.85 | ATIC (0.42) | ACLYATICCDK7CCNHMNAT1 | |
| SCHEMBL30286677 | 0.82 | MEN1 (0.40) | ACLYPIK3CAPTGES2 | |
| SCHEMBL20339149 | 0.82 | MEN1 (0.40) | ACLYPIK3CAPTGES2 | |
| SCHEMBL30286541 | 0.81 | ACLY (0.43) | ACLYATICNR3C1PGRNR3C2 | |
| SCHEMBL20354880 | 0.81 | ACLY (0.43) | ACLYATICNR3C1PGRNR3C2 | |
| SCHEMBL23610278 | 0.78 | NR3C1 (0.37) | ACLYATICCDK7CCNHMNAT1 | |
| SCHEMBL29830218 | 0.78 | NR3C1 (0.37) | ACLYATICCDK7CCNHMNAT1 | |
| SCHEMBL30286475 | 0.77 | ACLY (0.35) | ACLYATICSCN9ASCN1ASCN5A | |
| SCHEMBL20340286 | 0.77 | ACLY (0.35) | ACLYATICSCN9ASCN1ASCN5A | |
| SCHEMBL30286621 | 0.76 | CCR2 (0.40) | ACLYSCN9ASLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |