Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.42 |
| ▸ | HTR2A | P28223 | 9/20 | 0.42 |
| ▸ | HTR2B | P41595 | 7/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840037 | 0.84 | HTR2C (0.41) | HTR2CHTR2AHTR2BKCNH2 | |
| SCHEMBL10707953 | 0.79 | HTR2A (0.37) | HTR2CHTR2AHTR2BKCNH2CES1 | |
| SCHEMBL21692939 | 0.73 | HTR2C (0.41) | HTR2CHTR2AHTR2BBRD4CREBBP | |
| SCHEMBL20910802 | 0.69 | — | — | |
| SCHEMBL13075669 | 0.68 | MAOA (0.40) | BRD4CREBBP | |
| SCHEMBL7797306 | 0.68 | MEN1 (0.36) | BRD4CREBBP | |
| SCHEMBL9510659 | 0.68 | PNMT (0.42) | HTR2CHTR2AHTR2BKCNH2CES1 | |
| SCHEMBL25493558 | 0.68 | POLB (0.38) | HTR2CHTR2AHTR2BKCNH2BRD4 | |
| SCHEMBL20912271 | 0.68 | ALDH1A1 (0.40) | HTR2A | |
| Hydrochloric Acid SCHEMBL25197305 | 0.67 | POLB (0.37) | HTR2CHTR2AHTR2BKCNH2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894357-A | Skraup method for synthesizing 3, 8-dimethyl-7-chloroquinoline | 山东兴文工业技术研究院有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115894357-A | Skraup method for synthesizing 3, 8-dimethyl-7-chloroquinoline | 山东兴文工业技术研究院有限公司 | 2023-04-04 | — | — | CN | disclosed |