SCHEMBL28997148

SCHEMBL28997148

C=CCC(C)(C)C(=O)Nc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 2/20 0.50
PDK2 Q15119 2/20 0.50
PDK3 Q15120 2/20 0.50
PDK4 Q16654 2/20 0.50
TGM2 P21980 1/20 0.49
MMP8 P22894 1/20 0.48
MMP1 P03956 2/20 0.46
MMP2 P08253 2/20 0.46
MMP3 P08254 2/20 0.46
ALDH1A1 P00352 2/20 0.45
TSHR P16473 2/20 0.45
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11862689 0.84 NPSR1 (0.55) PDK1PDK2PDK3PDK4ALDH1A1
SCHEMBL2051018 0.83 TGM2 (0.52) PDK1PDK2PDK3PDK4TGM2
SCHEMBL11869894 0.81 RAB9A (0.56) ALDH1A1L3MBTL1MAPTGAARAB9A
SCHEMBL11871002 0.81 MAPK1 (0.43) PDK1PDK2PDK3PDK4ALDH1A1
SCHEMBL16847314 0.80 PDK1 (0.50) PDK1PDK2PDK3PDK4TGM2
SCHEMBL10530099 0.80 ALDH1A1 (0.51) PDK1PDK2PDK3PDK4TGM2
SCHEMBL11866396 0.80 KDM4E (0.43) PDK1PDK2PDK3PDK4ALDH1A1
SCHEMBL11864542 0.79 MAPT (0.41) TGM2MMP1MMP2MMP3ALDH1A1
SCHEMBL750651 0.79 RIPK1 (0.59) PDK1PDK2PDK3PDK4MMP8
SCHEMBL8321463 0.79 PDK1 (0.61) PDK1PDK2PDK3PDK4MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894323-A Method for self-cyclizing cyanation of enaminoaniline compound 湖北工业大学 2023-04-04 CN disclosed