Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28998282 | 0.90 | SYK (0.43) | SYKKDM4EALDH1A1LMNAADORA2A | |
| SCHEMBL19512883 | 0.82 | TSPO (0.43) | SYKKDM4EALDH1A1LMNAGRM5 | |
| SCHEMBL19475065 | 0.80 | ALDH1A1 (0.51) | SYKKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL28997458 | 0.75 | HPGD (0.48) | SYKKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL28272598 | 0.74 | TRPM8 (0.51) | SYKALDH1A1RAB9ANPC1TDP1 | |
| SCHEMBL19513124 | 0.72 | POLB (0.40) | KDM4EALDH1A1LMNAGRM5HSD17B10 | |
| SCHEMBL30285223 | 0.72 | POLB (0.40) | KDM4EALDH1A1LMNAGRM5HSD17B10 | |
| SCHEMBL19512884 | 0.72 | KDM4E (0.43) | KDM4EALDH1A1LMNAGRM5HSD17B10 | |
| SCHEMBL20914375 | 0.72 | RAB9A (0.54) | KDM4EALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL20936928 | 0.71 | KDM4E (0.42) | KDM4EALDH1A1LMNAGRM5HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311813-B | Palladium-catalyzed meta-C-H functionalized universal ligands | 斯克利普斯研究院 | 2023-02-28 | — | — | CN | disclosed |