Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 8/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.35 |
| ▸ | GCK | P35557 | 3/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601358 | 0.81 | SIRT6 (0.59) | SIRT6OXTRAVPR1AGCKAVPR2 | |
| SCHEMBL29005254 | 0.78 | NNMT (0.40) | MLYCD | |
| SCHEMBL29005159 | 0.77 | SIRT6 (0.42) | SIRT6 | |
| SCHEMBL29005276 | 0.75 | L3MBTL1 (0.43) | SIRT6OXTRAVPR1AMLYCD | |
| SCHEMBL30342136 | 0.75 | L3MBTL1 (0.43) | SIRT6OXTRAVPR1AMLYCD | |
| SCHEMBL2882770 | 0.74 | KMT2A (0.49) | OXTRAVPR1AMEN1KMT2A | |
| SCHEMBL17819683 | 0.71 | MEN1 (0.36) | SIRT6OXTRAVPR1AAVPR2MEN1 | |
| SCHEMBL2304361 | 0.71 | SIRT6 (0.50) | SIRT6OXTRAVPR1AMEN1KMT2A | |
| SCHEMBL24774974 | 0.71 | MLYCD (0.40) | SIRT6OXTRAVPR1AGCKMEN1 | |
| SCHEMBL30108431 | 0.71 | MLYCD (0.40) | SIRT6OXTRAVPR1AGCKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |