Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 12/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | USP14 | P54578 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28436430 | 0.84 | MAPT (0.40) | ELANEMAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28433432 | 0.82 | MAPT (0.38) | MAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL25178380 | 0.81 | MAPT (0.48) | MAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28776773 | 0.70 | TERT (0.32) | MAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28897005 | 0.68 | HSD17B10 (0.41) | POLBMAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL4661651 | 0.65 | MAPT (0.64) | POLBMAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL30451094 | 0.64 | KDM4E (0.42) | ELANEPOLBMAPTALDH1A1KCNH2 | |
| SCHEMBL31753433 | 0.63 | HRH3 (0.49) | ELANEPOLBALDH1A1KCNH2 | |
| SCHEMBL20663324 | 0.60 | PRKCZ (0.41) | ELANEMAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL20271371 | 0.60 | KDM4E (0.54) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920753-B | 6-fluoro-dihydropyran [2,3-c ] pyrazole derivative and synthetic method and application thereof | 华南理工大学 | 2023-06-20 | — | — | CN | disclosed |