Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28207258 | 0.78 | TSHR (0.36) | MEN1KMT2ATSHRALDH1A1HTT | |
| SCHEMBL28158503 | 0.76 | TERT (0.35) | KMT2ATSHRTERTFFAR4ALDH1A1 | |
| SCHEMBL27732171 | 0.73 | TERT (0.40) | HSD17B10MEN1KMT2ATSHRTERT | |
| SCHEMBL25178380 | 0.72 | MAPT (0.48) | MEN1KMT2ATSHRTERTALDH1A1 | |
| SCHEMBL27712033 | 0.70 | MAPT (0.38) | MEN1KMT2ATERTALDH1A1HTT | |
| SCHEMBL27369841 | 0.70 | ALDH1A1 (0.43) | MEN1KMT2ATERTALDH1A1HTT | |
| SCHEMBL27995307 | 0.69 | TERT (0.36) | MEN1KMT2ATERTSMN1; SMN2 | |
| SCHEMBL27995323 | 0.69 | TERT (0.34) | TSHRTERTALDH1A1HTTMAPT | |
| SCHEMBL29018666 | 0.68 | NR3C2 (0.41) | ALDH1A1HTTMAPTSMN1; SMN2POLB | |
| SCHEMBL27447779 | 0.68 | CD274 (0.46) | HSD17B10MEN1KMT2ATERTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111440181-A | Dipyrazolo seven-membered oxygen heterocyclic compound containing quinoline structure and synthetic method thereof | 烟台大学 | 2020-07-24 | — | — | CN | disclosed |