Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28436430 | 0.87 | MAPT (0.40) | MAPTALDH1A1HTTPRKCZSMN1; SMN2 | |
| SCHEMBL25178380 | 0.84 | MAPT (0.48) | MAPTALDH1A1HTTPRKCZSMN1; SMN2 | |
| SCHEMBL28523211 | 0.75 | KMT2A (0.47) | MAPTALDH1A1PRKCZSMN1; SMN2GAA | |
| SCHEMBL5805189 | 0.72 | MAPT (0.64) | MAPTALDH1A1HTTPRKCZSMN1; SMN2 | |
| SCHEMBL28776773 | 0.72 | TERT (0.32) | MAPTALDH1A1HTTSMN1; SMN2TERT | |
| SCHEMBL13666120 | 0.69 | LOX (0.34) | MAPTALDH1A1PRKCZPDE5AGAA | |
| SCHEMBL15720223 | 0.63 | FFAR1 (0.53) | MAPTPRKCZPDE5AGAAATM | |
| SCHEMBL28774867 | 0.62 | MEN1 (0.36) | MAPTALDH1A1HTTPRKCZSMN1; SMN2 | |
| SCHEMBL20663324 | 0.62 | PRKCZ (0.41) | MAPTALDH1A1HTTPRKCZSMN1; SMN2 | |
| SCHEMBL29349021 | 0.61 | HRH3 (0.42) | ALDH1A1SMN1; SMN2GAAATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111440181-A | Dipyrazolo seven-membered oxygen heterocyclic compound containing quinoline structure and synthetic method thereof | 烟台大学 | 2020-07-24 | — | — | CN | disclosed |