Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712033 | 0.87 | MAPT (0.38) | MAPTALDH1A1HTTSMN1; SMN2PRKCZ | |
| SCHEMBL28433432 | 0.87 | MAPT (0.38) | MAPTALDH1A1HTTSMN1; SMN2PRKCZ | |
| SCHEMBL27369841 | 0.87 | ALDH1A1 (0.43) | MAPTALDH1A1HTTSMN1; SMN2PRKCZ | |
| SCHEMBL28158503 | 0.85 | TERT (0.35) | MAPTALDH1A1HTTSMN1; SMN2TERT | |
| SCHEMBL29018666 | 0.84 | NR3C2 (0.41) | MAPTALDH1A1HTTSMN1; SMN2ELANE | |
| SCHEMBL28207258 | 0.83 | TSHR (0.36) | MAPTALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL28897005 | 0.78 | HSD17B10 (0.41) | MAPTALDH1A1HTTSMN1; SMN2TERT | |
| SCHEMBL27692022 | 0.77 | PRKCZ (0.45) | ALDH1A1HTTSMN1; SMN2PRKCZGAA | |
| SCHEMBL27778006 | 0.76 | EGFR (0.55) | MAPTALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL20663324 | 0.75 | PRKCZ (0.41) | MAPTALDH1A1HTTSMN1; SMN2PRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111440181-A | Dipyrazolo seven-membered oxygen heterocyclic compound containing quinoline structure and synthetic method thereof | 烟台大学 | 2020-07-24 | — | — | CN | disclosed |