Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | PDE6D | O43924 | 4/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29024485 | 0.89 | NPC1 (0.39) | LMNAFAAHMEN1KMT2ALTA4H | |
| SCHEMBL30478090 | 0.80 | FAAH (0.37) | HRH1LMNAFAAHMEN1KMT2A | |
| SCHEMBL29024639 | 0.78 | SLC16A3 (0.41) | HRH1GABRA1GABRB2PDE6DFAAH | |
| SCHEMBL7552154 | 0.78 | GABRA1 (0.48) | HRH1GABRA1GABRB2HTR2CSLC6A2 | |
| SCHEMBL29024487 | 0.78 | HRH1 (0.40) | HRH1GABRA1GABRB2PDE6DFAAH | |
| SCHEMBL30480300 | 0.70 | LMNA (0.41) | HRH1LMNAMEN1KMT2ALTA4H | |
| SCHEMBL29024483 | 0.70 | LMNA (0.40) | LMNAFAAHMEN1KMT2ALTA4H | |
| SCHEMBL29024489 | 0.67 | ABL1 (0.39) | PRMT5HTR2A | |
| SCHEMBL29024635 | 0.67 | TP53 (0.39) | LMNAFAAHLTA4HMAPTPRMT5 | |
| SCHEMBL8504734 | 0.67 | PRMT5 (0.49) | HTR2CSLC6A2SLC6A4SLC6A3PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354925-A | Pyrazole derivatives and use thereof | 江苏恩华药业股份有限公司 | 2023-06-30 | — | — | CN | disclosed |