Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 3/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29028719 | 0.85 | MAPT (0.46) | IDO1TDO2MPOLMNAMAPT | |
| SCHEMBL29028700 | 0.84 | MPO (0.47) | MPOLMNAMAPTHTT | |
| SCHEMBL29028711 | 0.84 | MPO (0.55) | IDO1TDO2MPOLMNAMAPT | |
| SCHEMBL29028769 | 0.84 | GRM5 (0.41) | ADORA2AMPOLMNAMAPTHTT | |
| SCHEMBL30473327 | 0.84 | MEN1 (0.41) | MPOLMNAMAPTMGLL | |
| SCHEMBL30473333 | 0.84 | MPO (0.55) | IDO1TDO2MPOLMNAMAPT | |
| SCHEMBL29028775 | 0.84 | MEN1 (0.41) | MPOLMNAMAPTMGLL | |
| SCHEMBL29028782 | 0.84 | LMNA (0.51) | ADORA3ADORA2AIDO1TDO2ADORA1 | |
| SCHEMBL29028722 | 0.84 | CTSK (0.46) | ADORA3LMNAMAPT | |
| SCHEMBL29028690 | 0.83 | MAPT (0.39) | GRM4MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332851-A | Cyanomethyl phenyl indazole compound and preparation method thereof | 河南中医药大学 | 2023-06-27 | — | — | CN | disclosed |